PDshop works with PayPal's new Payment Pro (previously known as Website Payments Pro).  

Here's how to get Started with PayPal Payments Pro and PDshop:

Get the features of an internet merchant account and payment gateway with Website Payments Pro. Control your checkout from start to finish by integrating PayPal Website Payments Pro with PDshop.

Step 1: Purchase & Download PDshop
Step 2: Set Up a Verified PayPal Business Account.
Step 3: Apply for Website Payments Pro.

1. Go to PayPal
2. Login to your PayPal Business Account    
3. Click the Merchant Services tab.
4. Click Website Payments Pro (U.S. Only).
5. Click Sign Up Now.
6. Fill in your information, and submit your application. Approval takes between 24 and 48 hours.
7. Once approved, accept the Pro billing agreement. Check the Getting Started section on the upper left of your account overview page.