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How to fix the "The handle is invalid OR Could not load file or assembly" message.
Sample Error
You may receive a message like this "The handle is invalid. (Exception from HRESULT: 0x80070006 (E_HANDLE))"

Or you may receive a message like this "Exception Details: System.Runtime.InteropServices.COMException"

Or you may receive a message like this "FileLoadException: Could not load file or assembly"
Solution or Workaround
The error indicates a server problem, unrelated to PDshop.  The error usually means your server is not able to load any assemblies (the dll files).  You should contact the web host or server administrator and have them restart your web server.
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